Thiosemicarbazone Iron Chelator - 6 Angebote vergleichen
| Preise | 2013 | 2014 | 2015 | 2021 |
|---|---|---|---|---|
| Schnitt | € 92,46 | € 93,47 | € 96,76 | € 79,00 |
| Nachfrage |
1
Symbolbild
Thiosemicarbazone Iron Chelator (2015)
DE PB NWISBN: 9783844386769 bzw. 3844386769, in Deutsch, LAP LAMBERT ACADEMIC PUB 01/04/2015, Taschenbuch, neu.
Von Händler/Antiquariat, Books2Anywhere [190245], Swindon, United Kingdom.
New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. This item is printed on demand.
New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. This item is printed on demand.
2
Symbolbild
Yu Yu
THIOSEMICARBAZONE IRON CHELATOR Evaluation of the anti-cancer activity and mechanisms of action
DE PB NWISBN: 9783844386769 bzw. 3844386769, in Deutsch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Von Händler/Antiquariat, BuySomeBooks [52360437], Las Vegas, NV, U.S.A.
Paperback. 220 pages. Dimensions: 8.7in. x 5.9in. x 0.5in.Previous studies demonstrated that thiosemicarbazone iron chelator possessed potent and selective anti-cancer activity. In this study, the in vitro and in vivo anti-tumor efficacy and tolerability of 2-benzoylpyridine thiosemicarbazone (BpT) iron chelators were examined. The BpT chelators were tested against human lung cancer cells in vitro and tumor xenografts in mice. The toxicity of Bp44mT and its effects on the expression of iron-regulated molecules involved in growth and cell cycle control were investigated. The results shown demonstrate the anti-tumor activity of the orally-active Bp44mT chelator, which was well tolerated in vivo. Furthermore, the cytotoxicity of thiosemicarbazones is likely to be mediated, in part, through their redox activity and effects on multiple thiol-containing systems. In terms of signal transduction, iron chelation may influence the MAPK signaling pathways via the thioredoxin-ASK1 signalosome. These results emphasize the importance of redox-activity of thiosemicarbazone chelators. Considering their potent anti-tumor activity, these investigations facilitate the future development of promising thiosemicarbazone iron chelators as anti-cancer agents. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.
Paperback. 220 pages. Dimensions: 8.7in. x 5.9in. x 0.5in.Previous studies demonstrated that thiosemicarbazone iron chelator possessed potent and selective anti-cancer activity. In this study, the in vitro and in vivo anti-tumor efficacy and tolerability of 2-benzoylpyridine thiosemicarbazone (BpT) iron chelators were examined. The BpT chelators were tested against human lung cancer cells in vitro and tumor xenografts in mice. The toxicity of Bp44mT and its effects on the expression of iron-regulated molecules involved in growth and cell cycle control were investigated. The results shown demonstrate the anti-tumor activity of the orally-active Bp44mT chelator, which was well tolerated in vivo. Furthermore, the cytotoxicity of thiosemicarbazones is likely to be mediated, in part, through their redox activity and effects on multiple thiol-containing systems. In terms of signal transduction, iron chelation may influence the MAPK signaling pathways via the thioredoxin-ASK1 signalosome. These results emphasize the importance of redox-activity of thiosemicarbazone chelators. Considering their potent anti-tumor activity, these investigations facilitate the future development of promising thiosemicarbazone iron chelators as anti-cancer agents. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.
3
Symbolbild
THIOSEMICARBAZONE IRON CHELATOR (2011)
DE PB NW RPISBN: 9783844386769 bzw. 3844386769, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, English-Book-Service - A Fine Choice [1048135], Waldshut-Tiengen, Germany.
This item is printed on demand for shipment within 3 working days.
This item is printed on demand for shipment within 3 working days.
4
Symbolbild
THIOSEMICARBAZONE IRON CHELATOR (2011)
DE PB NW RPISBN: 9783844386769 bzw. 3844386769, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, English-Book-Service - A Fine Choice [1048135], Waldshut-Tiengen, Germany.
This item is printed on demand for shipment within 3 working days.
This item is printed on demand for shipment within 3 working days.
5
Symbolbild
Thiosemicarbazone Iron Chelator (Paperback) (2011)
DE PB NW RPISBN: 9783844386769 bzw. 3844386769, in Deutsch, LAP Lambert Academic Publishing, Germany, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, The Book Depository EURO [60485773], London, United Kingdom.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
6
Thiosemicarbazone Iron Chelator (2011)
~EN PB NWISBN: 9783844386769 bzw. 3844386769, vermutlich in Englisch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Lieferung aus: Deutschland, Sofort lieferbar.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Lade…