New [14]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs
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New [1,4]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs (2014)
DE PB NW RP
ISBN: 9783659636950 bzw. 3659636959, in Deutsch, LAP Lambert Academic Publishing Dez 2014, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, AHA-BUCH GmbH [51283250], Einbeck, NDS, Germany.
This item is printed on demand - Print on Demand Titel. Neuware - Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake. 84 pp. Englisch.
This item is printed on demand - Print on Demand Titel. Neuware - Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake. 84 pp. Englisch.
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New [1,4]dihydropyridines for P-GP Mediated Efflux of Anticancer Drugs (Paperback) (2014)
DE PB NW RP
ISBN: 9783659636950 bzw. 3659636959, in Deutsch, Omniscriptum Gmbh Co. Kg, Taschenbuch, neu, Nachdruck.
Lieferung aus: Deutschland, Versandkostenfrei.
Von Händler/Antiquariat, The Book Depository EURO [60485773], Gloucester, UK, United Kingdom.
Language: English Brand New Book ***** Print on Demand *****.Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
Von Händler/Antiquariat, The Book Depository EURO [60485773], Gloucester, UK, United Kingdom.
Language: English Brand New Book ***** Print on Demand *****.Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
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New [1,4]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs
~EN PB NW
ISBN: 9783659636950 bzw. 3659636959, vermutlich in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Lieferung aus: Deutschland, Versandkostenfrei.
New [1,4]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs: Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake. Englisch, Taschenbuch.
New [1,4]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs: Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake. Englisch, Taschenbuch.
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New [1,4]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs
DE NW
ISBN: 9783659636950 bzw. 3659636959, in Deutsch, neu.
Lieferung aus: Deutschland, zzgl. Versandkosten.
Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
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New [1,4]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs
~EN NW AB
ISBN: 9783659636950 bzw. 3659636959, vermutlich in Englisch, neu, Hörbuch.
Lieferung aus: Österreich, Lieferzeit: 5 Tage, zzgl. Versandkosten.
Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
6
New [14]Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs
~EN PB NW
ISBN: 3659636959 bzw. 9783659636950, vermutlich in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
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New [1,4]Dihydropyridines for P-gp Mediated Effl (2014)
~EN PB NW
ISBN: 9783659636950 bzw. 3659636959, vermutlich in Englisch, Taschenbuch, neu.
Lieferung aus: Deutschland, Next Day, Versandkostenfrei.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
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