Formulation and Evaluation of Fast Dissolving Sublingual Tablet - Of Ivabradine Hydrochloride for reduction in ischemic condition in Stable Angina
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| Preise | 2014 | 2015 | 2017 |
|---|---|---|---|
| Schnitt | € 49,90 | € 53,65 | € 67,76 |
| Nachfrage |
1
Formulation and Evaluation of Fast Dissolving Sublingual Tablet
EN PB NWISBN: 9783659595363 bzw. 3659595365, in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu.
The present study was aimed to formulate and evaluate Fast Dissolving Sublingual Tablets of Ivabradine Hydrochloride, a selective If current inhibitor to reduce ischemic condition in Stable Angina. Efficacy of sublingual administration, higher permeability of drug and improvement in bioavailability achievement for drug were the factors that lead to the development of the present work. Compatibility studies of drug and polymer were performed by FTIR and demonstrated no interaction between drug and excipients. Tablets were prepared by direct compression using different concentration of Croscarmellose sodium and Crospovidone. Pre-compression parameters for blend were in the range. Prepared tablets were evaluated for disintegration time, wetting time, Water absorption ratio, %CDR and Ex-vivo permeability study. Formulation F6 (3% CCS, 4.5% CP) was found to be the optimized and showed disintegration time of 25 sec. In vitro drug release was found within 7 minutes and maximum relative permeability from F6 was up to 21 minutes. Dosage form also showed better stability criteria. From the results it was concluded that prepared FDTs executed faster release of IBH with improved characteristic.
2
Formulation and Evaluation of Fast Dissolving Sublingual Tablet (2014)
DE PB NWISBN: 9783659595363 bzw. 3659595365, in Deutsch, Lap Lambert Academic Publishing, Taschenbuch, neu.
Lieferung aus: Niederlande, 5-7 werkdagen.
bol.com.
The present study was aimed to formulate and evaluate Fast Dissolving Sublingual Tablets of Ivabradine Hydrochloride, a selective If current inhibitor to reduce ischemic condition in Stable Angina. Efficacy of sublingual administration, higher permeability of drug and improvement in bioavailability achievement for drug were the factors that lead to the development of the present work. Compatibility studies of drug and polymer were performed by FTIR and demonstrated no interaction between drug an... The present study was aimed to formulate and evaluate Fast Dissolving Sublingual Tablets of Ivabradine Hydrochloride, a selective If current inhibitor to reduce ischemic condition in Stable Angina. Efficacy of sublingual administration, higher permeability of drug and improvement in bioavailability achievement for drug were the factors that lead to the development of the present work. Compatibility studies of drug and polymer were performed by FTIR and demonstrated no interaction between drug and excipients. Tablets were prepared by direct compression using different concentration of Croscarmellose sodium and Crospovidone. Pre-compression parameters for blend were in the range. Prepared tablets were evaluated for disintegration time, wetting time, Water absorption ratio, %CDR and Ex-vivo permeability study. Formulation F6 (3% CCS, 4.5% CP) was found to be the optimized and showed disintegration time of 25 sec. In vitro drug release was found within 7 minutes and maximum relative permeability from F6 was up to 21 minutes. Dosage form also showed better stability criteria. From the results it was concluded that prepared FDTs executed faster release of IBH with improved characteristicTaal: Engels;Afmetingen: 7x229x152 mm;Gewicht: 181,00 gram;Verschijningsdatum: augustus 2014;ISBN10: 3659595365;ISBN13: 9783659595363; Engelstalig | Paperback | 2014.
bol.com.
The present study was aimed to formulate and evaluate Fast Dissolving Sublingual Tablets of Ivabradine Hydrochloride, a selective If current inhibitor to reduce ischemic condition in Stable Angina. Efficacy of sublingual administration, higher permeability of drug and improvement in bioavailability achievement for drug were the factors that lead to the development of the present work. Compatibility studies of drug and polymer were performed by FTIR and demonstrated no interaction between drug an... The present study was aimed to formulate and evaluate Fast Dissolving Sublingual Tablets of Ivabradine Hydrochloride, a selective If current inhibitor to reduce ischemic condition in Stable Angina. Efficacy of sublingual administration, higher permeability of drug and improvement in bioavailability achievement for drug were the factors that lead to the development of the present work. Compatibility studies of drug and polymer were performed by FTIR and demonstrated no interaction between drug and excipients. Tablets were prepared by direct compression using different concentration of Croscarmellose sodium and Crospovidone. Pre-compression parameters for blend were in the range. Prepared tablets were evaluated for disintegration time, wetting time, Water absorption ratio, %CDR and Ex-vivo permeability study. Formulation F6 (3% CCS, 4.5% CP) was found to be the optimized and showed disintegration time of 25 sec. In vitro drug release was found within 7 minutes and maximum relative permeability from F6 was up to 21 minutes. Dosage form also showed better stability criteria. From the results it was concluded that prepared FDTs executed faster release of IBH with improved characteristicTaal: Engels;Afmetingen: 7x229x152 mm;Gewicht: 181,00 gram;Verschijningsdatum: augustus 2014;ISBN10: 3659595365;ISBN13: 9783659595363; Engelstalig | Paperback | 2014.
3
Formulation and Evaluation of Fast Dissolving Sublingual Tablet: Of Ivabradine Hydrochloride for reduction in ischemic condition in Stable Angina (2014)
EN PB USISBN: 9783659595363 bzw. 3659595365, in Englisch, 116 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, gebraucht.
جديد من: £37.07 (8 ويقدم)
تستخدم من: £61.67 (1 ويقدم)
إظهار المزيد 9 ويقدم في Amazon.co.uk
Lieferung aus: Vereinigtes Königreich Großbritannien und Nordirland, Usually dispatched within 1-2 business days, بالإضافة إلى الشحن (في حالة شحنها).
Von Händler/Antiquariat, swestbooks.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Von Händler/Antiquariat, swestbooks.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
4
Formulation and Evaluation of Fast Dissolving Sublingual Tablet: Of Ivabradine Hydrochloride for reduction in ischemic condition in Stable Angina (2014)
EN PB NWISBN: 9783659595363 bzw. 3659595365, in Englisch, 116 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
جديد من: £37.07 (8 ويقدم)
تستخدم من: £61.67 (1 ويقدم)
إظهار المزيد 9 ويقدم في Amazon.co.uk
Lieferung aus: Vereinigtes Königreich Großbritannien und Nordirland, Usually dispatched within 1-2 business days, بالإضافة إلى الشحن (في حالة شحنها).
Von Händler/Antiquariat, Books-Please.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Von Händler/Antiquariat, Books-Please.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
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