Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle
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| Preise | Juli 16 | Okt. 16 | Okt. 19 |
|---|---|---|---|
| Schnitt | € 120,38 | € 41,01 | € 33,80 |
| Nachfrage |
1
Activation of Toll-Like Receptors 2 and 4 in skeletal muscle (2014)
~EN USISBN: 9783659217166 bzw. 3659217166, vermutlich in Englisch, 180 Seiten, gebraucht.
Toll-like receptor 2 (TLR2) and 4 (TLR4) are present in the plasma membrane of skeletal muscle where their functions are only partially understood. A variety of molecular components could activate TLR2 and TLR4, including non-esterified fatty acids (NEFA). NEFA, also are known to be released during endurance exercise. Likewise, endurance exercise may activate know downstream targets of TLR2 and TLR4 such as mitogen- activated protein kinase (MAPK) and nuclear factor-ĸB (NF-ĸB). The purpose of the present work was to investigate the plausible interaction between elevated plasma NEFA observed during endurance exercise and the MAPK activation mediated by TLR2 and TLR4. From a methodological point of view, three experimental models were used: myotubes cultured from C2C12 cells, soleus and tibialis muscle from C57BL/6J animals wild-type (WT) and transgenic tlr2-/- and tlr4-/- mice, and finally, muscle biopsies taken from the vastus lateralis of healthy and diabetics subjects. Our data supports a role for plasma NEFA in the activation of MAPK during endurance exercise. This activation may be mediated by TLR2 and TLR4 in skeletal muscle. 152x220, 0.295kg, 22.900/15.200/1.000.
2
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Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle (Paperback) (2014)
DE PB NW RPISBN: 9783659217166 bzw. 3659217166, in Deutsch, LAP Lambert Academic Publishing, United States, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, The Book Depository EURO [60485773], London, United Kingdom.
Language: English . Brand New Book ***** Print on Demand *****.Toll-like receptor 2 (TLR2) and 4 (TLR4) are present in the plasma membrane of skeletal muscle where their functions are only partially understood. A variety of molecular components could activate TLR2 and TLR4, including non-esterified fatty acids (NEFA). NEFA, also are known to be released during endurance exercise. Likewise, endurance exercise may activate know downstream targets of TLR2 and TLR4 such as mitogen- activated protein kinase (MAPK) and nuclear factor- B (NF- B). The purpose of the present work was to investigate the plausible interaction between elevated plasma NEFA observed during endurance exercise and the MAPK activation mediated by TLR2 and TLR4. From a methodological point of view, three experimental models were used: myotubes cultured from C2C12 cells, soleus and tibialis muscle from C57BL/6J animals wild-type (WT) and transgenic tlr2-/- and tlr4-/- mice, and finally, muscle biopsies taken from the vastus lateralis of healthy and diabetics subjects. Our data supports a role for plasma NEFA in the activation of MAPK during endurance exercise. This activation may be mediated by TLR2 and TLR4 in skeletal muscle.
Language: English . Brand New Book ***** Print on Demand *****.Toll-like receptor 2 (TLR2) and 4 (TLR4) are present in the plasma membrane of skeletal muscle where their functions are only partially understood. A variety of molecular components could activate TLR2 and TLR4, including non-esterified fatty acids (NEFA). NEFA, also are known to be released during endurance exercise. Likewise, endurance exercise may activate know downstream targets of TLR2 and TLR4 such as mitogen- activated protein kinase (MAPK) and nuclear factor- B (NF- B). The purpose of the present work was to investigate the plausible interaction between elevated plasma NEFA observed during endurance exercise and the MAPK activation mediated by TLR2 and TLR4. From a methodological point of view, three experimental models were used: myotubes cultured from C2C12 cells, soleus and tibialis muscle from C57BL/6J animals wild-type (WT) and transgenic tlr2-/- and tlr4-/- mice, and finally, muscle biopsies taken from the vastus lateralis of healthy and diabetics subjects. Our data supports a role for plasma NEFA in the activation of MAPK during endurance exercise. This activation may be mediated by TLR2 and TLR4 in skeletal muscle.
3
Symbolbild
Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle (2014)
~EN NW RPISBN: 9783659217166 bzw. 3659217166, vermutlich in Englisch, LAP Lambert Academic Publishing, neu, Nachdruck.
Von Händler/Antiquariat, Books2Anywhere [190245], Fairford, GLOS, United Kingdom.
New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
4
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Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle (2014)
~EN NW RPISBN: 9783659217166 bzw. 3659217166, vermutlich in Englisch, LAP Lambert Academic Publishing, neu, Nachdruck.
Von Händler/Antiquariat, Paperbackshop-US [8408184], Wood Dale, IL, U.S.A.
New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
5
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Activation of Toll-Like Receptors 2 and 4 in skeletal muscle (2017)
~EN PB NW RPISBN: 9783659217166 bzw. 3659217166, vermutlich in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, Ria Christie Collections [59718070], Uxbridge, United Kingdom.
PRINT ON DEMAND Book; New; Publication Year 2017; Not Signed; Fast Shipping from the UK.
PRINT ON DEMAND Book; New; Publication Year 2017; Not Signed; Fast Shipping from the UK.
6
Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle
EN USISBN: 9783659217166 bzw. 3659217166, in Englisch, LAP Lambert Academic Publishing, Lap Lambert Academic Publishing, Lap Lambert Academic Publishing, gebraucht.
Lieferung aus: Vereinigte Staaten von Amerika, zzgl. Versandkosten, in-stock.
Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle.
Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle.
7
Activation of Toll-Like Receptors 2 and 4 in Skeletal Muscle (2014)
EN PB NWISBN: 9783659217166 bzw. 3659217166, in Englisch, 180 Seiten, LAP Lambert Academic Publishing, Taschenbuch, neu.
Lieferung aus: Vereinigte Staaten von Amerika, Gewöhnlich versandfertig in 1 bis 2 Monaten. Versandkostenfrei.
Von Händler/Antiquariat, Amazon Global Store US.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Von Händler/Antiquariat, Amazon Global Store US.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
8
Activation of TollLike Receptors 2 4 in skeletal muscle (2014)
DE NWISBN: 9783659217166 bzw. 3659217166, in Deutsch, LAP Lambert Academic Publishing, neu.
Lieferung aus: Deutschland, Versandkosten nach: Deutschland, Versandkostenfrei.
Von Händler/Antiquariat, Magazin Aziya, [3458207].
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Von Händler/Antiquariat, Magazin Aziya, [3458207].
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
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